肌少性肥胖与癌症相关性的研究进展
Research Progress in the Association Between Sarcopenic Obesity and Cancer
徐春柳 1刘悦文 2郭琪 2于莹3
作者信息
- 1. 上海中医药大学研究生院, 上海 201203
- 2. 上海健康医学院康复学院, 上海 201318
- 3. 上海中医药大学研究生院, 上海 201203;上海健康医学院康复学院, 上海 201318
- 折叠
摘要
随着全球肥胖和老年人口数量的不断增加,肌少性肥胖的患病率持续上升,正成为全球流行的公共卫生问题.肌少性肥胖不仅会增加癌症的发生率,且在不同癌症类型中还与较差的临床结局有关,如手术并发症、死亡风险增加,甚至也可能对化疗产生影响,因此,肌少性肥胖逐渐成为癌症患者预后的重要指标.然而关于肌少性肥胖与癌症的关系,国内相关研究有限.本文旨在对肌少性肥胖的定义和诊断、肌少性肥胖与癌症的临床相关性及机制进行综述,以期为我国今后的临床实践提供参考.
Abstract
As the global prevalence of obesity and the elderly population continues to increase,the in-cidence of sarcopenic obesity is also on the rise and becoming a global public health concern.Sarcopenic obesity not only increases the incidence of cancer,but is also associated with poor clinical outcomes in various cancers,such as surgical complications,increased risk of death,and possibly even an impact on chemotherapy as well.Therefore,sarcopenic obesity is emerging as an important indicator of prognosis in cancer patients.However,there are limited relevant studies on the association between sarcopenic obesity and cancer in China.This article reviews the definition and diagnosis of sarcopenic obesity,the clinical correlation between sar-copenic obesity and cancer,and the potential mechanisms,with a view to providing a reference for future clini-cal practice in China.
关键词
肌少性肥胖/肥胖/癌症/肿瘤Key words
sarcopenic obesity/obesity/cancer/carcinoma引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据