实体肿瘤免疫检查点抑制剂治疗的影像学评估研究进展
Advances in Imaging-Based Evaluation of Solid Tumors Treated With Immune Checkpoint Inhibitors
杨尚颖 1刘新宇 1薛华丹 1金征宇 1何泳蓝 1李源2
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院放射科,北京 100730
- 2. 中国医学科学院 北京协和医学院 北京协和医院妇产科 国家妇产疾病临床研究中心,北京 100730
- 折叠
摘要
近年来,免疫检查点抑制剂(ICI)在多种实体肿瘤治疗领域应用卓有成效,但其引发的特殊应答模式和免疫相关不良反应降低了疗效评价的准确性.影像学是评估肿瘤免疫治疗的重要手段,不仅可以利用形态学和功能成像评价疗效,又可结合人工智能技术提供独特预测价值.本文探讨了各种影像手段和人工智能技术在评估实体肿瘤ICI治疗领域的价值以及相关研究进展.
Abstract
Immune checkpoint inhibitors have shown remarkable benefits in the treatment of solid tumors,while the occurrence of atypical response patterns and immune-related adverse events during treatment challenges the accuracy of therapeutic evaluation.Medical imaging is crucial for the evaluation of immunotherapy.It enables the assessment of treatment efficacy via both morphological and functional ways and offers unique a predictive val-ue when being combined with artificial intelligence.Here we review the recent research progress in imaging-based evaluation of solid tumors treated with immune checkpoint inhibitors.
关键词
免疫治疗/免疫检查点抑制剂/影像学/人工智能Key words
immunotherapy/immune checkpoint inhibitor/imaging/artificial intelligence引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据