Objective To evaluate the effects of ambient carbon particles exposure on autonomic nervous function and blood pressure(BP)in adults.Methods A panel study design was conducted,and 73 healthy adults were followed up 4 times from 24th November,2014 to 18th January,2016,collecting questionnaires information,fasting venous blood and urine samples,and prior 24-hour electrocardiogram and ambulatory BP data.We used generalized linear mixed models to analyze the associations of black carbon(BC),ultraviolet absorbing particulate matter(UVPM),and different sources of BC with heart rate variability(HRV)and BP.Results The results showed that acurate exposure to BC and UVPM were significantly associated with decreased HRV and increased BP.Decreased high frequency(HF),low frequency(LF)and very low frequency(VLF)of 5.2%(95%CI:-6.8--3.5)to 11.7%(95%CI:-14.9--8.3),increased LF/HF of 7.4%(95%CI:5.6-9.2)to 10.2%(95%CI:8.0-12.4)and increased BP of 0.8%(95%CI:0.3-1.3)to 1.9%(95%CI:1.1-2.7)were associated with interquartile spacing increases in BC and UVPM after cumulative exposure for 12h.Correlation analysis of black carbon from different sources with HRV and BP indexes showed that both biomass burning and black carbon from traffic sources were significantly associated with decreased HRV and increased BP and the effects of traffic source BC were stronger.Conclusions Carbon particles,especially traffic carbon particles can induce decreased HRV and increased BP in adults.
维普
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