Pulmonary tuberculosis is an infectious disease caused by the infection of Mycobacterium tuberculosis in the human lungs,which is the most common type of tuberculosis.Factors such as delayed early diagnosis,misdiagnosis,inappropriate treatment,delayed treatment and patients'autoimmune status worsen the disease and increase the risk of death.Long non-coding RNA(lncRNA)has emerged as potential new molecules affecting the diagnosis,treatment and prognosis of diseases,and has shown great potential and advantages in the diagnosis and treatment of pulmonary tuberculosis.Some studies have explored the potential role of lncRNA and their potential in monitoring the development of severe pulmonary tuberculosis.This article explores the biological functions of lncRNA in the progression of pulmonary tuberculosis,and the prospect of lncRNA as molecular biomarkers and targets for diagnosis and treatment of severe pulmonary tuberculosis is discussed.
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