摘要
分析基于CT的空洞特征对耐药肺结核(DR-PTB)及药物敏感肺结核(DS-PTB)患者影像诊断的价值,提高DR-PTB的CT诊断及鉴别诊断水平.回顾性收集明确诊断的323例DR-PTB患者和160例DS-PTB患者,对不同组别患者空洞的发生率、累及肺叶、空洞个数、结节(肿块)或实变中出现空洞、空洞的外内径大小及圆度、空洞壁的厚度进行统计学分析.结果显示,DR-PTB组的空洞发生率、空洞个数、多发空洞和累及3个及以上肺叶者的比例、肺内结节(肿块)中出现空洞的比例均明显高于DS-PTB组,且DR-PTB患者空洞分布更为广泛,DS-PTB与不同类型DR-PTB以及不同类型DR-PTB组间在空洞外径、内径和空洞壁厚度平均值方面的差异均具有统计学意义(P<0.05).CT空洞特征对DR-PTB与DS-PTB具有鉴别诊断价值.
Abstract
The diagnostic value of cavity features in CT for drug-resistant pulmonary tuberculosis(DR-PTB)and drug-sensitive pulmonary tuberculosis(DS-PTB)is analyzed for improving the CT diagnosis and differential diagnosis of DR-PTB.A retrospective study is conducted on 323 DR-PTB patients and 160 DS-PTB.DR-PTB and DS-PTB groups are compared in terms of the incidence of cavities,lung involvement,the number of cavities,the appearance of cavities in nodules(masses)or consolidation,the size and roundness of the outer and inner diameters of cavities,and the thickness of cavity walls.Compared with DS-PTB group,DR-PTB group has higher incidence of cavities,more cavities.The ratio of multiple cavities and 3 or more lung lobes involved and the ratio of cavities in pulmonary nodules(mass)in DR-PTB patients are significantly higher than those in DS-PTB group.Cavities are more widely distributed in DR-PTB patients.There are significant differences in CT cavity features,including the external diameter,internal diameter,and mean cavity wall thickness for DS-PTB and different types of DR-PTB,as well as within groups of different types of DR-PTB(P<0.05).CT features based on cavitation have significant values in distinguishing DR-PTB and DS-PTB.
基金项目
国家重点研发计划(2019YFE0121400)
深圳市科技计划(KQTD2017033110081833)
深圳市科技计划(JCYJ20190813153413160)
深圳市科技计划(JSGG20201102162802008)
深圳市科技计划(JCYJ20220531093817040)
广州市科技计划(2023A03J0536)
广州市科技计划(2024A03J0583)