CT功能成像在胃癌治疗前评估中的研究进展
Review on functional CT imaging for pretreatment assessment in gastric cancer
任铁柱 1陈倩倩 1张文娟 1邓娟 1苏鑫安 2徐敏 1徐媛 1孙嘉晨 1李玉凤 1周俊林1
作者信息
- 1. 兰州大学第二医院放射科/兰州大学第二临床医学院/甘肃省医学影像重点实验室/医学影像人工智能甘肃省国际科技合作基地,甘肃兰州 730030
- 2. 兰州大学第一医院风湿病科,甘肃兰州 730030
- 折叠
摘要
胃癌的发病率和死亡率均居世界恶性肿瘤前列,目前增强CT是胃癌术前诊断与评估的主要手段,但其多基于形态学评估,无法进行定量分析.以能谱CT及CT灌注成像为代表的功能成像技术发展迅速,其具有多种精准定量参数,有望弥补常规CT的缺陷.本文对能谱CT及CT灌注成像的基础原理、其在胃癌诊断、病理分型、分级、分期的评估以及疗效预测等方面的研究展开综述,旨在提高CT功能成像在胃癌治疗前评估中的认识.
Abstract
Both morbidity and mortality of gastric cancer are in the front rank among malignant tumors.At present,enhanced CT is served as an important imaging method for preoperative diagnosis and assessment of gastric cancer,but it is mostly based on morphological evaluation and unable to perform quantitative analysis.The functional imaging technology represented by energy spectral CT and CT perfusion imaging has a variety of quantitative parameters,which is expected to make up for the shortcomings of conventional CT.The review introduces the basic principles of energy spectral CT and CT perfusion imaging,and summarizes their applications in the diagnosis,pathological classification,grading,staging and efficacy prediction of gastric cancer,aiming to improve the understanding of functional CT imaging for the pretreatment assessment in gastric cancer.
关键词
胃癌/能谱CT/CT灌注/治疗前评估/综述Key words
gastric cancer/energy spectral CT/CT perfusion/pretreatment assessment/review引用本文复制引用
基金项目
国家自然科学基金(82071872)
国家自然科学基金(82102151)
甘肃省省级人才项目(青年个人项目)(甘组通字[2024]4号)
出版年
2024