中国医学物理学杂志2024,Vol.41Issue(10) :1211-1215.DOI:10.3969/j.issn.1005-202X.2024.10.004

最小子野宽度对原发性肝癌IMRT计划的剂量分布和实施精度的影响

Effects of minimum segment width on the execution efficiency and dose validation of IMRT plans for primary liver cancer

季洪兵 王凯 吴嘉慧 刘文晖
中国医学物理学杂志2024,Vol.41Issue(10) :1211-1215.DOI:10.3969/j.issn.1005-202X.2024.10.004

最小子野宽度对原发性肝癌IMRT计划的剂量分布和实施精度的影响

Effects of minimum segment width on the execution efficiency and dose validation of IMRT plans for primary liver cancer

季洪兵 1王凯 1吴嘉慧 1刘文晖1
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作者信息

  • 1. 福建医科大学孟超肝胆医院放疗科,福建 福州 350028
  • 折叠

摘要

目的:通过对原发性肝癌调强放射治疗(IMRT)计划的最小子野宽度参数进行研究,评价不同最小子野宽度下治疗计划的剂量分布和实施精度,为肿瘤患者放疗计划制作提供参考.方法:选取30例原发性肝癌患者资料,保持其它优化条件不变,改变最小子野宽度,分别为0.6、0.8、1.0、1.2、1.5 cm,对每例患者制作5个IMRT计划,比较5个计划的剂量分布、执行效率和Gamma通过率.结果:这5个计划的机器跳数和出束时间随着最小子野宽度的增加而减少;3 mm/3%、2 mm/2%阈值下的Gamma通过率则呈现增加趋势,且具有统计学差异(P<0.05).结论:研究所用的5个计划均能够用于临床治疗,在满足临床要求的同时,合理地设置IMRT计划中的最小子野宽度,可以降低机器跳数,缩短治疗时间,又可以提高治疗精度.

Abstract

Objective To evaluate the dose distribution and execution accuracy of intensity-modulated radiation therapy(IMRT)plans with different minimum segment widths for patients with primary liver cancer,thereby providing reference for the radiotherapy planning.Methods A retrospective study was conducted on 30 patients with primary liver cancer.With the other optimization condition unchanged,5 IMRT plans with minimum segment widths of 0.6,0.8,1.0,1.2 and 1.5 cm were made for each patient,and the dose distribution,execution efficiency and gamma passing rate of the 5 plans were compared.Results The monitor units and delivery time of the 5 plans decreased with increasing minimum segment width,while the gamma passing rates at 3 mm/3%and 2 mm/2%tended to increase,with statistical differences(P<0.05).Conclusion The 5 plans in the study can be used for clinical treatment.While meeting the clinical requirements,reasonably setting the minimum segment width in IMRT plan can reduce monitor units,shorten delivery time,and improve treatment accuracy.

关键词

原发性肝癌/最小子野宽度/实施精度/剂量验证/Gamma通过率

Key words

primary liver cancer/minimum segment width/execution efficiency/dose verification/gamma passing rate

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基金项目

福建省自然科学基金(2022J011290)

福建医科大学启航基金(2021QH1161)

出版年

2024
中国医学物理学杂志
南方医科大学,中国医学物理学会

中国医学物理学杂志

CSTPCD
影响因子:0.483
ISSN:1005-202X
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