Correlation between 24 h urinary protein quantitation level and pregnancy outcome in patients with severe early onset preeclampsia
Objective To investigate the relationship between 24h urinary protein quantitation level and pregnancy outcome in patients with early onset of severe preeclampsia (SPE).Methods Accordoring to the 24h urine protein quantitation level,126patients with early-onset SPE hospitalized in People's Hospital of Meizhou City from January 2010 to January 2015 were divided into group A (≥ 5g) and group B (＜ 5g).And patients of two groups were given expectant treatment,pregnancy outcomes and complications of mother and infant were compared.Results There was no significant difference in time of expectant treatment between the two groups (P ＞ 0.05),The main complications of puerperae were placental abruption,HELLP syndrome,eclampsia,severe fetal growth restriction,hydrothorax and ascite,hypoalbuminemia,and there were no significant differences between the two groups (P ＞0.05),and there were no significant differences in the expectant treatment time and cesarean section rate(P ＞ 0.05).Check in NICU rate,incidence of respiratory distress syndrome of the group A were higher than those of the group B (P ＜ 0.05).Gestational weeks,weight,and Apgar score at birth and intracranial hemorrhage rate,failure rate of bronchial lung development,the perinatal death rate of two groups had no significant difference(P ＞ 0.05).Conclusion 24 h urine protein quantitation level should not be used as a single indicator to determine the severity and termination of pregnancy in patients with early onset SPE,so as to improve the prognosis of newborns,gestational age,clinical manifestation,fetal maturity and so on should be considered.
severe preeclampsia24 h urinary protein quantitationexpectant treatmentpregnancy outcome
NETL
NSTL
万方数据
维普
