Study on the correlation between two-dimensional and three-dimensional ultrasound quantification indicators of chorionic bumps and early pregnancy outcomes
Objective To explore the clinical significance of transluminal two-dimensional ultrasound(2D-TVS)and three-dimensional ultrasound(3D-TVS)in evaluating chorionic bumps(CB).Methods A total of 11042 pregnant women who underwent early pregnancy examinations at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 2019 to April 2022 were included in the retrospective analysis.Among them,46 cases of CB were included in the CB group.421 other early pregnant women were selected and included in the control group,and their early pregnancy outcomes were compared.The CB group was divided into the miscarriage subgroup and intrauterine live fetus subgroup according to early pregnancy outcomes.The CB group was divided into CB = 1 subgroup and CB>1 subgroup according to the CB number.2D-TVS records the gestational sac(GS),the anteroposterior diameter,upper and lower diameters,left and right diameters and number of CB,and calculated GS average,CB average and CB/GS average ratio.3D-TVS obtains the GS and CB volumes and calculates the CB/GS volume ratio.To compare the ultrasound indicators of two subgroups and analyse the correlation between ultrasound indicators and early pregnancy outcomes.Results The incidence of CB was0.42%,the probability of miscarriage at early-stage gestation was 55.6% in the CB group,which were significantly higher than that in the control group(5.1%),and the difference was statistically significant(P<0.05).Compare the GS average,GS volume,CB average,CB volume and CB number between the abortion group and the intrauterine live fetus group,the difference was not statistically significant(P>0.05).The CB/GS average ratio and the volume of CB/GS in the abortion group were larger than those in the intrauterine live fetus group,and the differences were statistically significant(P<0.05).The volume ratio(CB/GS)was correlated with miscarriage at early-stage gestation(P<0.05),the correlation coefficients was0.409,while there was no correlation in other indexes(P>0.05).There was no statistically significant difference in the abortion rate between CB =1 group(58.6%)and CB>1group(42.9%)(P>0.05).Conclusions The CB/GS average ratio and CB/GS volume ratio are associated with early pregnancy outcomes.CB/GS volume ratio is positively correlated with early pregnancy miscarriage rate.CB,as an ultrasound sign with poor prognosis in early pregnancy,has the potential to increase the risk of miscarriage in early pregnancy.
NETL
NSTL
维普
万方数据
