The clinical efficacy of long follicular phase protocol and long luteal phase protocol in different age groups with normal ovarian reserve function
Objective The clinical application effects of long follicular phase protocol and long luteal phase protocol in different age groups with normal ovarian reserve function were compared.Methods Retrospective analysis of the clinical data of patients undergoing IVF-ET/ICSI in the Department of Reproductive Medicine,Affiliated Hospital of Zunyi Medical University from January 2018 to December 2021.The clinical data of 1196 assisted pregnancy patients were selected according to the inclusion and exclusion criteria.According to the different ovulation induction protocol,they were divided into 934 cases in the follicular phase long protocol group and 262 cases in the luteal phase long protocol group.According to the age,they were divided into<35 years old group and 35～40 years old group.The general data,ovulation induction indexes,laboratory indexes and clinical outcomes of the two ovulation induction protocol in different age groups were observed.Results ① Age<35 years old group:The total amount of Gn,Gn days,clinical pregnancy rate,cleavage clinical pregnancy rate and cumulative pregnancy rate in the follicular phase long protocol group were higher than those in the luteal phase long protocol group,and the difference was statistically significant(P<0.05).② Age 35～40 years old group:The total amount of Gn,Gn days,positive rate of hCG,clinical pregnancy rate,cleavage stage clinical pregnancy rate and cumulative pregnancy rate in the follicular phase long protocol group were higher than those in the luteal phase long protocol group,and the difference was statistically significant(P<0.05).Conclusion In the different age groups with normal ovarian reserve function,the total amount and days of Gn used in the long follicular phase protocol were higher than those in the long luteal phase protocol,but it could significantly improve the clinical pregnancy rate,cleavage clinical pregnancy rate and cumulative pregnancy rate,and obtain better clinical efficacy.
NETL
NSTL
万方数据
