Analysis of the therapeutic effect of the combination of Qingre Xiaoyong Zhitong Recipe and photon therapy in the incision infection after cesarean section
Objective To analyze the effect of Qingre Xiaoyong Zhitong Recipe application combined with photon therapy on the expression of soluble myeloid cell trigger receptor-1(sTREM-1),interleukin-1(IL-1)and interleukin-8(IL-8)in patients with wound infection after caesarean section.Methods Patients with incision infection after cesarean section who received treatment at Zhangjiakou Maternal and Child Health Hospital from June 2021 to June 2023 were selected as the research subjects.The photon therapy was used as the photon therapy group,the Qingre Xiaoyong Zhitong Recipe was used as the patch group,and the application of Qingre Xiaoyong Zhitong Recipe combined with photon therapy was used as the combination group,50 cases in each group.Compared the incision pain,cervical microcirculation status(proportion of clear cervical blood vessels,capillary diameter,microvascular diameter,blood flow perfusion),immune stress indicators[cortisol(Cor),CD4+T lymphocytes,CD8+T lymphocyte ratio],and serum levels of sTREM-1,IL-1,and IL-8 expression in three groups of patients,and analyzed the wound healing and treatment effectiveness.Results Compared with the photon therapy group,the incision pain score in the combination group and the patch group was reduced,the proportion of clear cervical local blood vessels,capillary diameter,microvascular diameter,blood perfusion,CD4+T lymphocytes were increased,and the expression levels of Cor,CD8+T lymphocytes,serum sTREM-1,IL-1 and IL-8 were decreased,and the healing time was shortened(P<0.05).Compared with the patch group,the incision pain score of the combination group was decreased,the proportion of clear cervical local blood vessels,capillary diameter,microvascular diameter,blood perfusion,CD4+T lymphocytes were increased,the expression levels of Cor,CD8+T lymphocytes,serum sTREM-1,IL-1,IL-8 were decreased,and the healing time was shortened(P<0.05).Compared with the photon therapy group,the total wound healing rate and total effective rate of the combination group and the patch group were increased(P<0.05);compared with the patch group,the total wound healing rate and total effective rate of the combination group were increased(P<0.05).Conclusion The application of Qingre Xiaoyong Zhitong Recipe combined with photon therapy can improve the cervical microcirculation and the abnormal immune stress of patients with incision infection after caesarean section,inhibit the synthesis of sTREM-1,IL-1 and IL-8,thus promoting incision healing,alleviating pain and eliminating infection symptoms,and the effect is ideal.