Correlational study between fetal weight with gestational diabetes mellitus and maternal fetal serum trace element content
Objective To explore the relationship between fetal growth weights and the content of trace elements in maternal blood and neonatal cord blood in pregnant women with gestational diabetes mellitus(GDM).Methods The GDM fetal weight cohort was constructed.According to the inclusion and exclusion criteria,selected postpartum women who underwent cesarean section due to non pathological surgical indications at Nanjing Maternal and Child Health Hospital from March to August 2022,27 cases in the normal control group(group C)and 38 cases in the GDM group(group G),including 19 cases in the GDM age-appropriate infants group(group GA)and 19 cases in the GDM macrosomia group(group GM).The contents of 9 trace elements in all maternal peripheral blood and newborn umbilical venous blood detected at the earlier stage of the cohort were compared to explore the correlation between GDM fetal weight and trace elements.Results Compared with group C,the serum arsenic content in group G postpartum women decreased;the zinc and arsenic elements in cord blood decreased.Compared with the group GA,the selenium content in the serum of mothers in the group GM decreased while the lead content increased;and arsenic increased in cord blood.Conclusion The decrease in arsenic and selenium content in maternal serum may be related to the occurrence and development of GDM and macrosomia.Appropriate supplementation of some trace elements during pregnancy is expected to reduce the incidence rate of GDM and reduce the risk of delivery of GDM macrosomia.
gestational diabetes mellitusmacrosomiatrace elements
NETL
NSTL
万方数据
