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围产期抑郁与焦虑的交叉滞后分析

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目的 探讨围产期抑郁与焦虑症状之间的动态变化情况及双向预测关系.方法 本研究系前瞻性纵向研究,选取2022年10月1日至2023年10月1日于川北医学院附属医院产检的妊娠晚期孕妇进行追踪调查.分别在妊娠晚期(T1)与产后6周(T2)采用爱丁堡产后抑郁量表(Edinburgh Postnatal Depression Scale,EPDS)、焦虑自评量表(Self-rating Anxiety Scale,SAS)对研究对象进行心理评估.分析围产期抑郁与焦虑症状的筛查情况,进一步通过重复测量方差分析(ANOVA)及Pearson相关分析研究两者之间的差异及相关性,最后使用Mplus 8.3软件构建交叉滞后模型,分析在T1与T2的围产期抑郁与焦虑症状之间的纵向关联及预测方向.结果 共纳入219例研究对象,T1的抑郁与焦虑症状发生率分别为31.1%、6.8%,T2的发生率分别为33.8%、10.5%;T1与T2抑郁、焦虑症状的发生率及SAS量表平均得分差异均有统计学意义(P<0.001);T1与T2的抑郁、焦虑症状之间均呈显著正相关(P<0.001),且T1抑郁和焦虑症状均可显著正向预测T2抑郁与焦虑症状(P<0.001).结论 在T1与T2两个时间段的围产期抑郁与焦虑症状之间存在相互影响和双向预测的关系.
Cross-lagged analysis of perinatal depression and anxiety
Objective To explore the dynamic changes and bidirectional predictive relationship between perinatal depression and anxiety symptoms.Methods This study is a prospective longitudinal study,and the pregnant women in the third trimester of pregnancy who were examined in the Affiliated Hospital of North Sichuan Medical College from October 1,2022 to October 1,2023 were followed up.Edinburgh Postnatal Depression Scale(EPDS)and Self-rating Anxiety Scale(SAS)were used to evaluate the psychology of research subjects in the third trimester of pregnancy(T1)and six weeks after delivery(T2)respectively.Analyzed the screening of perinatal depression and anxiety symptoms,and the differences and correlation between them were further studied by repeated measurement analysis of variance(ANOVA)and Pearson correlation analysis.Finally,a cross-lag model was constructed by using Mplus 8.3 software to analyze the vertical correlation and prediction direction between perinatal depression and anxiety symptoms at T,and T2.Results A total of 219 subjects were included.The incidence rates of depression and anxiety symptoms were 31.1%and 6.8%respectively at T,,33.8%and 10.5%at T2.The incidence of depression and anxiety symptoms and the average score of SAS between T,and T2 were statistically significan(P<0.001).There was a significant positive correlation between T1 and T2 symptoms of depression and anxiety(P<0.001),and symptoms of depression and anxiety at T,can significantly positively predict symptoms of depression and anxiety at T2(P<0.001).Conclusions There is a relationship of mutual influence and bidirectional prediction between depression and anxiety of pregnant women in T,and T2.

perinataldepressionanxietycross-lagged analysis

谭欣林、黄玥、甘艳琼、袁玉红、廖宇佳、田小兵、漆洪波、石琪

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637000 四川 南充,川北医学院附属医院产科

637000 四川 南充,川北医学院

637770 四川 南充,南充市身心医院临床心理科

401147 重庆,重庆医科大学附属妇女儿童医院妇产科

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围产期 抑郁 焦虑 交叉滞后分析

国家工业和信息化部-国家卫生健康委员会5G+医疗健康应用试点项目

JKZX2022-5G03

2024

中国计划生育和妇产科
中国医师协会 四川省医学情报研究所

中国计划生育和妇产科

CSTPCD
影响因子:1.116
ISSN:1674-4020
年,卷(期):2024.16(9)