Cross-lagged analysis of perinatal depression and anxiety
Objective To explore the dynamic changes and bidirectional predictive relationship between perinatal depression and anxiety symptoms.Methods This study is a prospective longitudinal study,and the pregnant women in the third trimester of pregnancy who were examined in the Affiliated Hospital of North Sichuan Medical College from October 1,2022 to October 1,2023 were followed up.Edinburgh Postnatal Depression Scale(EPDS)and Self-rating Anxiety Scale(SAS)were used to evaluate the psychology of research subjects in the third trimester of pregnancy(T1)and six weeks after delivery(T2)respectively.Analyzed the screening of perinatal depression and anxiety symptoms,and the differences and correlation between them were further studied by repeated measurement analysis of variance(ANOVA)and Pearson correlation analysis.Finally,a cross-lag model was constructed by using Mplus 8.3 software to analyze the vertical correlation and prediction direction between perinatal depression and anxiety symptoms at T,and T2.Results A total of 219 subjects were included.The incidence rates of depression and anxiety symptoms were 31.1%and 6.8%respectively at T,,33.8%and 10.5%at T2.The incidence of depression and anxiety symptoms and the average score of SAS between T,and T2 were statistically significan(P<0.001).There was a significant positive correlation between T1 and T2 symptoms of depression and anxiety(P<0.001),and symptoms of depression and anxiety at T,can significantly positively predict symptoms of depression and anxiety at T2(P<0.001).Conclusions There is a relationship of mutual influence and bidirectional prediction between depression and anxiety of pregnant women in T,and T2.