首页|超声GI-RADS分级与肿瘤标志物在小儿卵巢肿瘤良恶性鉴别中的价值

超声GI-RADS分级与肿瘤标志物在小儿卵巢肿瘤良恶性鉴别中的价值

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目的 探讨超声影像报告与数据系统(GI-RADS)分级与肿瘤标志物对小儿卵巢肿瘤良恶性鉴别的应用价值.方法 回顾性分析2019年1月至2022年10月延安大学附属医院诊治的小儿卵巢肿瘤患者的临床资料.比较良恶性肿瘤的肿瘤标志物水平、超声影像特征,绘制ROC曲线分析各项诊断方法效能.结果 恶性组肿瘤直径大于良性组,阻力指数低于良性组,血流峰值速度、大乳头状突起高度、壁厚高于良性组,且以实性为主、血流信号Ⅱ~Ⅲ级、单发、宽基底为主,存在腹水以及中心性血流(P<0.05).恶性组CA199(82.61±9.14)KU/L、CA125(69.42±6.15)KU/L 高于良性组(P<0.05).超声 GI-RADS 分级诊断准确率84.67%,CA199诊断准确率74.00%,CA125诊断准确率76.00%,联合诊断准确率96.00%.同时,经ROC曲线分析,超声GI-RADS分级、CA199、CA125及三项联合诊断卵巢肿瘤良恶性的AUC分别为0.832、0.690、0.677、0.939.结论 在鉴别小儿卵巢肿瘤良恶性时,联合超声GI-RADS分级和肿瘤标志物可提高诊断准确率.
The value of ultrasound GI-RADS grading and tumor markers in differentiating benign and malignant ovarian tumors in children
Objective Exploring the application value of the Ultrasound Imaging Reporting and Data System(GI-RADS)grading and tumor markers in the differentiation of benign and malignant ovarian tumors in children.Methods Retrospective analysis of clinical data of pediatric ovarian tumor patients treated at Affiliated Hospital of Yan'an University from January 2019 to October 2022.Compared the levels of tumor markers and ultrasound imaging features of benign and malignant tumors,and drew ROC curves to analyze the effectiveness of various diagnostic methods.Results The diameter of the malignant group tumor was larger than that of the benign group,the resistance index was lower than that of the benign group,and the peak blood flow velocity,height of the large papillary process,and wall thickness were higher than those of the benign group.The tumor was mainly solid,with blood flow signals of Ⅱ~Ⅲgrade,single and wide base,and there was ascites and central blood flow(P<0.05).The CA199(82.61±9.14)KU/L and CA125(69.42±6.15)KU/L in the malignant group were higher than those in the benign group(P<0.05).The accuracy of ultrasound GI-RADS grading diagnosis was 84.67%,the accuracy of CA199 diagnosis was 74.00%,the accuracy of CA125 diagnosis was 76.00%,and the accuracy of combined diagnosis was 96.00%.Meanwhile,according to ROC curve analysis,the AUC for the combined diagnosis of benign and malignant ovarian tumors using ultrasound GI-RADS grading,CA199,and CA125 were 0.832,0.690,0.677,and 0.939,respectively.Conclusion Combining ultrasound GI-RADS grading and tumor markers can improve diagnostic accuracy in distinguishing benign and malignant ovarian tumors in children.

ultrasoundimage report and data systemtumor markersovarian tumoridentify

任伟、王巧云、刘青、张鑫

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716000 陕西 延安,延安大学附属医院超声医学科

超声 影像报告与数据系统 肿瘤标志物 卵巢肿瘤 鉴别

2024

中国计划生育和妇产科
中国医师协会 四川省医学情报研究所

中国计划生育和妇产科

CSTPCD
影响因子:1.116
ISSN:1674-4020
年,卷(期):2024.16(9)