Effect of Wen Yang Huo Xue Hua Xi Tang combined with dydrogesterone tablets in preventing postoperative recurrence of endometrial polyps
Objective To observe the effect of Wen Yang Huo Xue Hua Xi Tang combined with dydrogesterone tablet on preventing recurrence of endometrial polyps patients after operation.Methods 108 patients with endometrial polyps who underwent hysteroscopic resection at the Department of Obstetrics and Gynecology in Hebei Provincial Veterans General Hospital from February 2019 to October 2021 were selected as the study subjects.They were randomly divided into the control group and the observation group using a random number table method,with 54 cases in each group.The control group received postoperative oral treatment with dydrogesterone tablet,while the observation group received treatment with Wen Yang Huo Xue Hua Xi Tang while taking dydrogesterone tablets orally.Evaluated two groups of traditional Chinese medicine syndrome scores,endometrial thickness,levels of sex hormone indicators,levels of inflammatory factors,and postoperative recurrence rate.Results After 3 months of treatment,the total score of traditional Chinese medicine syndromes in the observation group was lower than that in the control group(P<0.05);the endometrial thickness of the two groups of patients after treatment,3 months after treatment,and 9 months after treatment was significantly lower than before treatment,and the endometrial thickness of the observation group was significantly lower than the corresponding time thickness of the control group in the three time periods(P<0.05);the levels of estradiol(E2)decreased in both groups after treatment and 3 months after treatment,and the observation group was significantly lower than the control group,while the levels of progesterone(P)increased in both groups,and the observation group was higher than the control group(P<0.05);serum levels of interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)decreased in two groups of patients after treatment and 3 months after treatment,and the observation group was lower than the control group(P<0.05);the disease recurrence rate of the observation group patients at 12 months after surgery(1.85%)was significantly lower than that of the control group(12.96%),and the difference was statistically significant(P<0.05).Conclusion The combination of Wen Yang Huo Xue Hua Xi Tang and dydrogesterone tablets may improve clinical efficacy and reduce postoperative recurrence rate by regulating the levels of sex hormones and inflammatory factors.
endometrial polypshysteroscopic resectiondydrogesterone tabletsWen Yang Huo Xue Hua Xi Tang