首页|胃镜下高频电氩气切术与胃镜下黏膜切除术治疗胃息肉的临床疗效和安全性的对比观察

胃镜下高频电氩气切术与胃镜下黏膜切除术治疗胃息肉的临床疗效和安全性的对比观察

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目的 对比胃镜下高频电氩气切术与胃镜下黏膜切除术(EMR)治疗胃息肉的临床疗效和安全性.方法 选择90例胃息肉患者作为研究对象,将其随机分为A组(n=45,91枚息肉)和B组(n=45,94枚息肉).A组行胃镜下高频电氩气切术治疗,B组行EMR术治疗.比较两组临床疗效、围术期指标和术后7 d不良反应的发生情况,以及术前和术后7 d的血清学检测指标.结果 A组治疗总有效率、1次息肉切除率均高于B组,术中出血量、手术时间、住院时间均少/短于B组,术后7d不良反应的发生率低于B组(均P<0.05).术后7d,两组胃蛋白酶原Ⅰ、胃泌素-17水平均高于术前,且A组均高于B组(均P<0.05);两组胃蛋白酶原Ⅱ水平差异无统计学意义(P>0.05).结论 与EMR术相比,胃镜下高频电氩气切术可更有效地治疗胃息肉,安全性更高,损伤更小,胃黏膜修复更快,术后恢复时间更短.
Clinical efficacy and safety of endoscopic high-frequency electrotomy with argon and endoscopic mucosal resection in the treatment of gastric polyps:a comparative observation
Objective To compare the clinical efficacy and safety between endoscopic high-frequency electrotomy with argon and endoscopic mucosal resection(EMR)in the treatment of gastric polyps.Methods A total of 90 patients with gastric polyps were selected as the study subjects and randomly divided into group A(n=45,91 polyps)and group B(n=45,94 polyps).Group A was treated with endoscopic high-frequency electrotomy with argon,and group B was treated with EMR.The clinical efficacy,perioperative indexes,incidence of adverse reactions within 7 days after surgery,and serological indicators before surgery and 7 days after surgery were compared between the two groups.Results The total effective rate of treatment and the 1-time polyps resection rate in group A were higher than those in group B,while the intraoperative blood loss,operation time,and length of hospital stay were less/shorter than those in group B,and the incidence of adverse reactions within 7 days after surgery was lower than that in group B(all P<0.05).Seven days after surgery,the levels of pepsinogen Ⅰ and gastrin-17 in the two groups were higher than those before surgery,the abovementioned indexes in group A were higher than those in group B(all P<0.05),but there was no statistically significant difference in the pepsinogen Ⅱ level between the two groups(P>0.05).Conclusion Compared with EMR,endoscopic high-frequency electrotomy with argon can treat gastric polyps more effectively,with higher safety,less damage,faster gastric mucosal repair,and shorter postoperative recovery time.

Gastric polypEndoscopic high-frequency electrotomy with argonGastrin-17Endoscopic mucosal resection

李海欣

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广东医科大学附属第二医院,湛江市 524000

胃息肉 胃镜下高频电氩气切术 胃泌素-17 胃镜下黏膜切除术

2024

内科
广西壮族自治区医学科学情报研究所

内科

影响因子:0.905
ISSN:1673-7768
年,卷(期):2024.19(2)
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