Intravenous ultrasound for evaluating atherosclerotic plaque characteristics of different type traditional Chinese medicine syndrome of coronary heart disease
Objective To observe characteristics of atherosclerotic plaque of coronary heart disease(CHD)with different traditional Chinese medicine(TCM)syndrome type based on intravenous ultrasound(IVUS).Methods Data of 116 CHD patients were retrospectively analyzed.The patients were divided into syndrome of blood stasis due to qi deficiency(n=33),syndrome of blockade of phlegm-turbidity(n=42)as well as syndrome of intermin-gled phlegm and blood stasis(n=41)according to TCM syndrome differentiation.IVUS was performed to compare lesion vessel and plaque characteristics among different syndromic types of CHD.Results The lipid pool area,extravascular elastic membrane area,remodeling index,plaque eccentricity index of CHD with syndrome of blood stasis due to qi deficiency were all larger than those of syndrome of blockade of phlegm-turbidity as well as syndrome of intermin-gled phlegm and blood stasis(all P＜0.05).The proportion of fibrous-fatty within plaques of syndrome of blood stasis due to qi deficiency was bigger than that of syndrome of intermin-gled phlegm and blood stasis(P＜0.05).The lipid pool area,extravascular elastic membrane area and plaque eccentricity index of CHD of syndrome of blockade of phlegm-turbidity were smaller than,while the proportion of necrotic core within plaques was bigger than those of syndrome of intermin-gled phlegm and blood stasis(all P＜0.05).Conclusion Atherosclerotic plaque characteristics in CHD with different TCM syndrome types were different,and the plaque stability of syndrome of blood stasis due to qi deficiency was the worst.
coronary diseasemedicine,Chinese traditionalultrasonographytreatment based on syndrome differentiation
万方数据
维普
