摘要
目的 基于超声弹性成像观察2型糖尿病(T2DM)患者股四头肌肌腱改变.方法 回顾性分析80例T2DM患者(T2DM组)和80名健康人(对照组);比较2组一般资料及超声弹性成像参数,包括股四头肌肌腱近段、远段及中段与同侧股前脂肪垫比值[即应变率(SR)]的差异,并分析其与病程及糖化血红蛋白(HbA1c)的相关性.结果 T2DM组空腹血糖及HbA1c明显高于对照组(P均＜0.05).相比对照组,T2DM组股四头肌肌腱近段、中段及远段SR均明显增高(P均＜0.05),以远段和近段增高更为显著(t=6.01、5.92).T2DM组股四头肌肌腱近段、中段及远段SR与病程(r=0.45、0.20、0.43)和HbA1c(r=0.44、0.40、0.33)均呈正相关(P均＜0.05).结论 T2DM患者股四头肌肌腱SR明显增高,且与病程及HbA1c水平呈正相关.
Abstract
Objective To observe the changes of quadriceps tendon in type 2 diabetes mellitus(T2DM)patients based on ultrasonic elastography.Methods Data of 80 T2DM patients(T2DM group)and 80 healthy subjects(control group)were retrospectively analyzed.The general information and ultrasound elastography parameters,including strain ratio(SR)of the ratio of the proximal,middle and distal segments of quadriceps tendon and ipsilateral anterior femoral fat pad were compared between groups,while the correlations of the above SR with the disease course of T2DM and glycosylated hemoglobin(HbA1c)were explored.Results Fasting blood glucose and HbA1c in T2DM group were both significantly higher than those in control group(both P＜0.05).Compared with control group,SR of the proximal,middle and distal segments of quadriceps tendon in T2DM group were all significantly higher(all P＜0.05),especially the distal and proximal segments(t=6.01,5.92).In T2DM group,SR of the proximal,middle and distal segments of quadriceps tendon were positively correlated with the disease course of T2DM(r=0.45,0.20,0.43,all P＜0.05)and HbA1c(r=0.44,0.40,0.33,all P＜0.05).Conclusion SR of quadriceps tendon in T2DM patients significantly increased and positively correlated with the course of disease and HbA1c.
基金项目
扬州市重点研发项目(社会发展)(YZ2022119)
扬州市中医院院级科技项目(2022YNKT06B)
维普
万方数据