Echocardiography myocardial work indicators for predicting prognosis of patients with resistant hypertension
Objective To screen echocardiography myocardial work indicators for predicting prognosis of patients with resistant hypertension(RH).Methods Totally 67 RH patients were prospectively enrolled,and baseline echocardiography data were collected.Follow-up was conducted until 4 years after examination or when adverse events occurred.The baseline data were compared between those with adverse event(group A)and without adverse events(group B),and the myocardial work indicators able to be used to predict adverse events in RH patients were screened.Results During follow-up period,3 cases were lost,21 cases had and 43 cases did not had adverse events.The proportion of left ventricular wall thickening and global wasted work(GWW)in group A were both higher,while the left ventricular global longitudinal strain(LVGLS)and the global work efficiency in group A were both lower than those in group B(all P＜0.05).Left ventricular wall thickening was an independent risk factor for adverse events in RH patients(OR=6.96,P＜0.05;HR=5.026,P＜0.05).Taken-14.50％,109.00 mmHg％and 12 mm as the cutoff value,respectively,the area under the curve(AUC)of LVGLS,GWW and left ventricular wall thickening for predicting adverse events in RH patients was 0.791,0.732 and 0.664,respectively,of the combination of the above three was 0.857,and the latter was superior to AUC of GWW and left ventricular wall thickening(both P＜0.05).Conclusion LVGLS,GWW and thickness of left ventricular wall could be used to predict adverse events in RH patients.
万方数据
维普
