The third-generation dual-source CT Sn 100 kVp scanning for guiding percutaneous core needle biopsy of pulmonary nodules
Objective To observe the efficacy,safety and radiation dose of the third generation dual-source CT Sn 100 kVp scanning for guiding percutaneous needle biopsy of pulmonary nodules.Methods Totally 210 patients with solitary pulmonary nodule were prospectively enrolled and randomly assigned into ultra-low-dose CT group(ULDCT,n=100,underwent CT guidance of Sn 100 kVp and 70 mAs scanning)or standard-dose CT group(SDCT,n=110,underwent CT guidance of 110 kVp and 50 mAs scanning).The successful rate of sampling,diagnostic efficacy,incidence of complications,imaging qualities and radiation doses were compared between groups.Results The success sampling and biopsy rate in ULDCT group was 97.00％,not significantly different with that in SDCT group(98.18％,P＞0.05).No significant difference of diagnostic sensitivity,specificity,accuracy of biopsy after successful sampling nor incidence of complication was detected between groups(all P＞0.05).Compared with those in SDCT group,ULDCT group had undifferentiated mean CT scan range(P=0.520)but lower mean volume CT dose index,total dose-length product and effective dose(all P＜0.05),and imaging qualities of ULDCT met the requirements of percutaneous needle biopsy.Conclusion Using the third-generation dual-source CT Sn 100 kVp scanning could simultaneously ensure the diagnostic accuracy and safety of percutaneous needle lung biopsy and significantly reduce radiation dose.
NETL
NSTL
万方数据
