首页|基于5.0T MRI定量肝脏质子密度脂肪分数

基于5.0T MRI定量肝脏质子密度脂肪分数

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目的 观察5.0T MRI用于定量肝脏质子密度脂肪分数(PDFF)的价值.方法 前瞻性对30名受试者分别行5.0T、3.0T、1.5T肝脏化学位移编码(CSE)MR扫描,测量CSE-PDFF;之后行5.0T、1.5T MR波谱(MRS),测量MRS-PDFF.分析不同方法所测肝脏PDFF的一致性,评估5.0T MRI定量肝脏PDFF的价值.结果 以不同场强MR设备所测肝脏CSE-PDFF总体一致性良好(ICC均>0.75,P均<0.001);基于5.0T MR与3.0T、1.5T MR所测肝脏CSE-PDFF 的一致性均好(ICC=0.989、0.992,P 均<0.001).基于 5.0T MR 所测 CSE-PDFF 与 5.0T、1.5T MR 所测 MRS-PDFF 一致性均好(ICC 均>0.75,P 均<0.001);其中,5.0T MR 所测 CSE-PDFF 与 MRS-PDFF 一致性好(ICC=0.988,P<0.001),5.0T MR 所测 CSE-PDFF 与 1.5T MR 所测 MRS-PDFF 一致性好(ICC=0.978,P<0.001).结论 5.0T MRI对定量肝脏PDFF具有较高价值.
5.0T MRI for quantifying proton density fat fraction of liver
Objective To observe the value of 5.0T MRI for quantifying proton density fat fraction(PDFF)of liver.Methods Liver chemical shift encoded(CSE)MR scanning were prospectively performed using 5.0T,3.0T and 1.5T scanner in 30 volunteers,respectively,and CSE-PDFF were measured.Then MR spectroscopy(MRS)were performed using 5.0T and 1.5T scanner,respectively,and MRS-PDFF were also measured.The consistency of liver PDFF measured on different images was observed,and the value of 5.0T MRI for liver PDFF was analyzed.Results The overall consistencies of liver CSE-PDFF measured with 5.0T,3.0T and 1.5T MR scanner were all good(all ICC>0.75,all P<0.001).The consistency of liver CSE-PDFF based on 5.0T and 3.0T,1.5T MR scanner were both good(ICC=0.989,0.992,both P<0.001).The overall consistencies of CSE-PDFF based on 5.0T MR and MRS-PDFF based on 5.0T and 1.5T MR were both good(both ICC>0.75,both P<0.001).CSE-PDFF had good consistency with MRS-PDFF based on same 5.0T MR scanner(ICC=0.988,P<0.001),and CSE-PDFF based on 5.0T had good consistency with MRS-PDFF based on 1.5T MR scanner(ICC=0.978,P<0.001).Conclusion 5.0T MRI had high value for quantifying liver PDFF.

liveradipose tissuemagnetic resonance imagingfat fractionprospective studies

刘建宪、王振松、王鑫、田宁、陈鹏、于丹、杨燕兴、程传力、邹超、甘洁

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山东大学附属山东省立第三医院影像中心,山东济南 250032

北京联影智能影像技术研究院,北京 100094

上海联影医疗科技股份有限公司,上海 201807

深圳先进技术研究院劳特伯生物医学成像研究中心,广东深圳 518055

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脂肪组织 磁共振成像 脂肪分数 前瞻性研究

山东省医药卫生科技项目

202209010957

2024

中国医学影像技术
中国科学院声学研究所

中国医学影像技术

CSTPCD北大核心
影响因子:0.763
ISSN:1003-3289
年,卷(期):2024.40(5)
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