首页|异基因造血干细胞移植后耶氏肺孢子菌肺炎与巨细胞病毒性肺炎CT表现

异基因造血干细胞移植后耶氏肺孢子菌肺炎与巨细胞病毒性肺炎CT表现

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目的 比较异基因造血干细胞移植(allo-HSCT)后耶氏肺孢子菌肺炎(PCP)与巨细胞病毒性肺炎(CMVP)的CT表现.方法 回顾性分析21例allo-HSCT后PCP(PCP组)及26例CMVP患者(CMVP组),比较其CT表现.结果 组间病灶(包括磨玻璃影及结节)分布方式、肺囊肿、病情达最重时间、30天病灶吸收>50%占比、病灶完全吸收占比及首次磨玻璃影病灶总严重程度评分差异均有统计学意义(P均<0.05).结论 allo-HSCT后PCP与CMVP的CT表现相似,但前者磨玻璃影分布范围较广、其内多见肺囊肿而预后较好,后者磨玻璃影分布范围相对较小、而结节多呈弥漫分布且预后较差.
CT manifestations of pneumocystis jirovecii pneumonia and cytomegalovirus pneumonia after allogeneic hematopoietic stem cell transplantation
Objective To compare CT manifestations of pneumocystis jirovecii pneumonia(PCP)and cytomegalovirus pneumonia(CMVP)after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Methods Totally 21 PCP patients(PCP group)and 26 CMVP patients(CMVP group)after allo-HSCT were retrospectively enrolled,and CT findings were compared between groups.Results Significant differences of distribution patterns of ground glass opacity(GGO)and nodule lesions,lung cysts,the time of condition reached most severe,the proportion of cases with lesions absorption more than 50% within 30 days,of cases with lesions completely absorbed and the first total severity score(TSS)of GGO were found between groups(all P<0.05).Conclusion CT manifestations of PCP and CMVP after allo-HSCT were somehow similar,but GGO distributed widerly,with more lung cysts and better prognosis in the former,while GGO distrubuted relatively limitted with diffuse nodules and poor prognosis in the latter.

pneumoniahematopoietic stem cell transplantationtomography,X-ray computed

程敏、陈皓、孙烨、曹旭阳、洪楠

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北京大学人民医院放射科,北京 100044

北京丰台右安门医院放射科,北京 100069

肺炎 造血干细胞移植 体层摄影术,X线计算机

2024

中国医学影像技术
中国科学院声学研究所

中国医学影像技术

CSTPCD北大核心
影响因子:0.763
ISSN:1003-3289
年,卷(期):2024.40(7)
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