首页|68Ga-FAPI PET/CT及PET/MR诊断恶性肿瘤研究进展

68Ga-FAPI PET/CT及PET/MR诊断恶性肿瘤研究进展

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成纤维细胞激活蛋白抑制剂(FAPI)可与肿瘤间质内高表达的成纤维细胞激活蛋白特异性结合;68Ga-FAPI不参与肿瘤细胞葡萄糖代谢.68Ga-FAPI PET/CT及PET/MR可用于多部位恶性肿瘤显像,对于诊断与鉴别诊断具有独特优势.本文围绕68Ga-FAPI PET/CT及PET/MR诊断恶性肿瘤研究进展进行综述.
Research progresses of 68Ga-FAPI PET/CT and PET/MR for diagnosing malignant tumors
Fibroblast activation protein inhibitors(FAPI)can specifically bind to fibroblast activation protein,which is highly expressed in tumor stroma,and 68Ga-FAPI do not get involved into the procedure of glucose metabolism in tumor cells.68Ga-FAPI PET/CT and PET/MR can be used for displaying malignant tumors at various sites and play a unique role for diagnosis and differential diagnosis.The research progresses of 68 Ga-FAPI-based PET/CT and PET/MR for diagnosing malignant tumors were reviewed in this article.

neoplasmsgallium radioisotopespositron-emission tomographytomography,X-ray computedmagnetic resonance imaging

李天悦、马拓、赵新明、张召奇、王建方、戴萌、赵秀娟、张敬勉

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河北医科大学第四医院核医学科,河北 石家庄 050011

肿瘤 镓放射性同位素 正电子发射断层显像术 体层摄影术,X线计算机 磁共振成像

2024

中国医学影像技术
中国科学院声学研究所

中国医学影像技术

CSTPCD北大核心
影响因子:0.763
ISSN:1003-3289
年,卷(期):2024.40(11)