Application and Research Progress of Ultrafine Pulverization Technology in Preparation of Traditional Chinese Medicines
This review introduces the principles,structures and development directions of commonly used ultrafine pulverizing equipment.The application of ultrafine pulverization technology in preparation of traditional Chinese medicines is systematically outlined,including enhancing the wall breaking rate,refining the physicochemical properties,promoting the extraction,elevating the efficacy of medicinal components,and streamlining subsequent processing of traditional Chinese medicines.Then,the combining principles of particle design technology with traditional Chinese medicine powder technology are elucidated.Additionally,methods for determining particle size and evaluating cell wall breaking rates,as well as the conduction of pharmacokinetic-pharmacodynamic studies of traditional Chinese medicine ultrafine powder are proposed.Ultimately,the development prospects of ultrafine pulverization technology are discussed,and the issues that urgently need resolution are summarized,with the aim of providing references for the application of ultrafine pulverization technology in preparation of traditional Chinese medicines.
ultrafine pulverization technologyultrafine pulverizing equipmenttraditional Chinese medicinepowderparticle design technologyquality evaluation