Double-layer tablets are a novel dosage form which attract wide attention.With bilayer structures,double-layer tablets can enhance drug efficacy,reduce adverse drug reactions and improve patient compliance by combination medication or adjusting the release rate.This review summarizes the research progress of double-layer tablets in recent years,generalizes the characteristics,preparation methods and classification of double-layer tablets,and introduces its clinical applications with case studies.It is hoped to provide a reference for the research and development of double-layer tablets.
double-layer tabletimmediate-release layersustained-release layerefficacysolid dosage form
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