微流控芯片应用于皮肤领域研究的创新探索
Innovative Explorations of Microfluidic Chips Applied to the Field of Skin Research
胡阳阳 1罗华菲1
作者信息
- 1. 中国医药工业研究总院医药先进制造国家工程研究中心,上海 201203
- 折叠
摘要
微流控芯片在药物递送、即时检测、细胞分选和器官芯片等领域已有广泛应用.文章以微流控芯片在皮肤相关研究领域中的应用为切入点,主要介绍了微流控芯片中微流体流动的基本原理、芯片的制造材料和构成,以及微流控芯片在药物经皮递送系统开发、经皮检测和皮肤病建模中的应用,以期为经皮递药系统制备、健康监测以及寻找体外皮肤模型的研究者提供参考.
Abstract
Microfluidic chips have been widely used in drug delivery,real-time detection,cell sorting and organ chips.Based on the application of microfluidic chips in skin-related research fields,this review mainly introduces the basic principles of microfluidic flow in microfluidic chips,the manufacturing materials and compositions of chips,and the application of microfluidic chips in the development of drug transdermal delivery systems,percutaneous detection and modeling of skin diseases.It is hoped that this review can provide references for researchers in the preparation of transdermal drug delivery systems,health monitoring and looking for in vitro skin model.
关键词
微流控芯片/经皮递送/可穿戴式微流控芯片/皮肤芯片/研究进展Key words
microfluidic chip/transdermal delivery/wearable microfluidic chip/skin-on-a-chip/research progress引用本文复制引用
出版年
2024
NETL
NSTL
万方数据