Nanofiltration,as a technology without thermal effect is suitable for the purification and separation of heat-sensitive components of traditional Chinese medicines(TCM).However with the transition of separation environment from water to organic solution,the physical and chemical properties of nanofiltration separation layer change,which makes it difficult for the separation model suitable for aqueous solution environment to guide the orderly separation of organic solution.Based on the charge effect,dissolution-diffusion effect and pore size screening effect,combined with the properties and production rules of TCM components,the regulation rules of complex solution environment can be explored.In this paper,the application features and challenges of nanofiltration separation technology in the field of TCM are analyzed around the complex solution environment.The nanofiltration separation mechanism in complex solution environment is reviewed,which provide a reference for improving the applicability of nanofiltration technology.
关键词
纳滤/复杂溶液/中药制剂/分离机制/应用特点/研究进展
Key words
nanofiltration/complex solution/Chinese medicine preparation/separation mechanism/application feature/research progress