Periodontitis is a chronic infection of the periodontal tissue caused by the biofilm of dental plaque,which can lead to tooth loosening,gum atrophy.Its main pathogenic bacteria include Porphyromonas gingivalis.Based on the abundant blood vessels in the periodontal pocket,local delivery of antibacterial drugs can make drugs act directly on the lesion site and improve the bioavailability.This paper focuses on introducing biodegradable local drug delivery systems that have been marketed for the treatment of periodontitis,and summarizes the relevant drug prescriptions and preparation processes,hoping to provide a reference for the development of new dosage forms for the treatment of periodontitis.
periodontitislocal drug deliverysustained-releaseantibacterial drugresearch progress
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