Due to various physiological and anatomical barriers in the human eye,the bioavailability of topical ophthalmic preparations,such as eye drops,is less than 5％.While the bioavailability of drug-eluting contact lenses can achieve 50％,and the products have the dual functions of drug release and visual correction.This paper reviews the research progress of preparation methods,sterilization and quality evaluation of drug-eluting contact lenses.The advantages and disadvantages of different preparation methods in drug loading and release,as well as the critical functional attributes of drug-eluting contact lenses are emphasized,hoping to provide some references for promoting the clinical application of medicated contact lenses.
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