To provide a experimental basis for the determination of the period of validity and identify drugs storage conditions, the stability of metadoxine tablets were determined. Methods: Its contents were determined with HPLC Determination. The stability of metadoxine tablets were determined by the light test, the accelerate test and long-term tests, application of the formula of Arrhenius and the statistical principle for equation to calculate K25℃ and predict drug valid. Results: Metadoxine tablets were not stable in the case of light. The results of long-term tests is consistented with the predicated drug valid. Conclusions: The predicated effective deadline is twenty-four monthes at room temperature, protected from light.
Metadoxine TabletsStabilityPeriod of ValidityLight TestAccelerate TestLong-term Tests
NETL
NSTL
维普
万方数据
