Regulatory effect of Qingre Tiaotang Decoction on hazardous factors of type 2 diabetes mellitus patients with the damp-heat syndrome
Objective To study the regulatory effect of Qingre Tiaotang Decoction on hazardous factors of type 2 diabetes mellitus(T2DM)patients with damp-heat syndrome.Methods A total of 76 T2DM patients with damp-heat syndrome admitted to and treated in Lanzhou Hospital of Traditional Chinese Medicine from January 2021 to April 2022 were selected,and divided into control group and study group by digital sampling.36 cases in the control group were treated with metformin,and 40 cases in the study group were treated with Qingre Tiaotang Decoction on the basis of treatment in the control group.Both groups were treated for two courses of treatment.The indicators of glucose metabolism,lipid metabolism,vibration perception threshold(VPT),ankle brachial index(ABI)and traditional Chinese medicine(TCM)syndrome score were compared in each group before and after treatment.The glucose metabolism indicators included C-peptide,fasting insulin(INS),fasting blood glucose(FBG),insulin resistance index(IRI),glycosylated hemoglobin(GHB),standard deviation of blood glucose(SDBG),and largest amplitude of glycemic excursions(LAGE).Lipid metabolism indicators included triglyceride(TG),total cholesterol(TC),low-density lipoprotein(LDL),and high-density lipoprotein(HDL).Results After treatment,the GHB and LAGE in the control group were lower than those before treatment.The GHB,IRI,LAGE,TC,and LDL of the study group were lower than those before treatment,and the levels of C-peptides,FBG,IRI,TC,LDL,and TCM syndrome were lower than those of the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in VPT and ABI values between the two groups(P>0.05).The conversion rates of syndrome types between the two groups were 27.78％and 20.00％,and the incidence of adverse reactions was 13.89％and 15.00％,with no statistically significant difference(P>0.05).Conclusion Qingre Tiaotang Decoction combined with metformin can regulate the hazardous factors of T2DM with damp-heat syndrome,and will not increase the adverse reactions.
万方数据
维普
