Research progress on the effect and mechanism of Rhodiola rosea in preventing Alzheimer's disease
Alzheimer's disease(AD)is a progressive and irreversible neurodegenerative disease that can interfere with the activities of consciousness and intelligence.The specific pathogenesis of these neurodegenerative diseases is not yet clear,but the loss of neural cell function,abnormal accumulation of amyloid structures,hyperphosphorylation of the microtubule-associated protein tau(tua proteins),poor mitochondrial composition and function,chronic inflammatory response,oxidative stress,etc.in the patient's brain are currently considered the most common pathological features of these diseases,and cognitive and learning and memory impairment,as well as executive dysfunction are also important clinical manifestations.Many scientific studies have shown that many chemical substances in traditional Chinese medicine Rhodiola rosea,such as Salidroside,Rhodiosin,etc.,can have excellent neuroprotective effects on AD-type neurodegenerative diseases through pharmacological means such as antioxidant,anti-inflammation,antiapoptosis,etc.