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基于文献分析中医药治疗血精症的用药规律研究

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目的 探究中医药治疗血精症的用药规律,为临床用药提供依据.方法 在中国知网中检索建库至2023 年 3 月中医药治疗血精症的相关文献,建立处方用药数据库,使用Excel、SPSS等软件进行药物统计、关联规则分析、聚类分析等.结果 共纳入文献 90 篇,收集处方 98 首,涉及中药 167 种,高频药物共 27 味,前五位依次是生地黄、黄柏、牡丹皮、甘草、墨旱莲;药物以清热药、止血药和补虚药为多,药性多寒、平,药味多甘、苦,归经入肝、肾两经为主;关联分析得到 5 对核心药对,其中"黄柏-知母"支持度和置信度均最高;聚类分析得到 6 类药物组方.结论 中医药治疗血精症多从肝肾出发,清热止血补虚三法并用,二至丸合知柏地黄汤是治疗血精症的核心处方,临床上随证加减.
Study on the medication rules of traditional Chinese medicine in the treatment of hemospermia based on literature analysis
Objective To explore the medication rules of traditional Chinese medicine in the treatment of hemospermia and provide a basis for clinical medication.Methods The relevant literature on the treatment of hematospermia with traditional Chinese medicine was retrieved on CNKI,with the retrieval time limit from the establishment of the database to March 2023.A prescription medication database was established,and software such as Excel and Statistical Product and Service Solutions(SPSS)was used for drug statistics,association rule analysis,cluster analysis,etc.Results A total of 90 articles were included,and 98 prescriptions were collected,involving 167 types of traditional Chinese medicine.A total of 27 high-frequency drugs were involved,with the top five being Radix rehmanniae,Cortex phellodendri,Cortex moutan,Glycyrrhiza uralensis,and Herba eclipta.The drugs mainly included heat-clearing drugs,hemostatic drugs,and tonifying drugs.The properties of the drugs are often cold and mild,and the taste is often sweet and bitter.They mainly belong to the liver and kidney meridians.Association analysis obtained 5 core drug pairs,with"Cortex phellodendri-Rhizoma Anemarrhenae"having the highest support and confidence levels.Cluster analysis yielded 6 types of drug formulations.Conclusion Traditional Chinese medicine for the treatment of hemospermia often starts from the liver and kidney and combines the three methods of clearing heat,stopping blood,and tonifying deficiency.The combination of Erzhi Pill and Zhibai Dihuang Decoction is the core prescription for the treatment of hemospermia and can be adjusted according to the symptoms in clinical practice.

Traditional Chinese medicineHemospermiaMedication rulesLiterature analysis

叶有骏、王莉、张婷、钱鑫、徐新宇、崔云、吴骏

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浙江中医药大学第三临床医学院,浙江杭州 310053

上海中医药大学附属岳阳中西医结合医院中医外科,上海 200437

浙江中医药大学附属宁波中医院中医外科,浙江宁波 315010

中医药 血精症 用药规律 文献分析

崔云全国名老中医药专家传承工作室建设项目浙江省中医药科学研究基金项目

国中医药人教函[2022]75号2022ZB311

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(1)
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