首页|抗精神性药物联合非药物治疗对精神分裂症患者认知功能的影响研究

抗精神性药物联合非药物治疗对精神分裂症患者认知功能的影响研究

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目的 探讨抗精神性药物联合非药物治疗精神分裂症患者的效果以及对患者认知功能的影响。方法选取 2020 年 1 月至 2022 年 12 月福州神经精神病防治院收治的 80 例精神分裂症患者作为研究对象,根据随机数表法分为参照组与治疗组,每组各 40 例。参照组行抗精神性药物治疗,治疗组在参照组基础上联合非药物治疗。比较两组精神症状、认知功能、行为习惯以及生活质量。结果 治疗后,治疗组阴性症状指标评分均低于参照组,差异有统计学意义(P<0。05);治疗组可重复成套神经心理状态测量量表(RBANS)评分、生活质量以及积极因素评分高于参照组,差异有统计学意义(P<0。05);治疗组消极因素评分低于参照组,差异有统计学意义(P<0。05)。结论 抗精神性药物联合非药物治疗精神分裂症能有效改善患者精神症状以及认知功能,提高生活质量,纠正不良习惯,应用价值较高。
Study on the effect of antipsychotic drugs combined with non-drug therapy on cognitive function in patients with schizophrenia
Objective To explore the efficacy of antipsychotic drugs combined with non-drug therapy in patients with schizophrenia and their impact on the cognitive function of patients.Methods A total of 80 patients with schizophrenia admitted to Fuzhou Neuro-Psychiatric Hospital from January 2020 to December 2022 were selected as the study subjects.They were divided into a reference group and a treatment group based on a random number table method,with 40 patients in each group.The reference group received antipsychotic drug treatment,while the treatment group received non-drug treatment based on the antipsychotic drug treatment.The psychiatric symptoms,cognitive function,behavioral habits,and quality of life of the two groups were compared.Results After treatment,the negative symptom index score of the treatment group was lower than that of the reference group,with statistically significant differences(P<0.05).The repeatable battery for the assessment of neuropsychological status(RBANS)scores,quality of life scores,and positive factor scores of the treatment group were higher than those of the reference group,with statistically significant differences(P<0.05).The negative factor score of the treatment group was lower than that of the reference group,with a statistically significant difference(P<0.05).Conclusion Antipsychotic drugs combined with non-drug therapy for schizophrenia can effectively improve patients'psychiatric symptoms and cognitive function,improve quality of life,correct bad habits,and have high application value.

SchizophreniaAntipsychotic drugsNon-drugPsychiatric symptomsCognitive functionQuality of life

何鑫森

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福建省福州神经精神病防治院精神科,福建福州 350000

精神分裂症 抗精神性药物 非药物 精神症状 认知功能 生活质量

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(1)
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