The role and research progress of exosomes in the diagnosis and treatment of liver failure
Liver failure is acute and chronic liver damage caused by various factors such as viruses,alcohol,drugs,and autoimmune factors,which can lead to serious disorders in the body's synthesis,detoxification,metabolism,and biological transformation functions.It is common in clinical practice and has a high mortality rate.Exosomes are membrane-derived nanoscale extracellular vesicles that carry components such as proteins,nucleic acids,and lipids,and can be released and ingested by most liver cells.In the state of liver failure caused by various reasons,while exosomes continue to secrete,their contents may undergo qualitative or quantitative changes.After transmitting biological information to receptor cells,it can promote changes in receptor cell-related pathways,thereby accelerating or delaying the occurrence and development of liver diseases,playing an indispensable role in cellular communication.This review summarizes the main biological characteristics of exosomes,,and their broad prospects for future applications in liver diseases.
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