Experimental research progress on anti-atherosclerosis of effective components of Caesalpinia sappan lignum
The traditional Chinese medicine Caesalpinia sappan lignum has a mild nature,a sweet and salty taste,and is beneficial for regulating the heart,liver,and spleen meridians.It has the effects of promoting blood circulation,removing blood stasis,and relieving swelling and pain.Pharmacological studies have found that the effective components of Caesalpinia sappan lignum can be roughly divided into brazilin,protosappanin,homoisoflavonoids,chalcones,etc.,which have the effects of lowering blood lipids,anti-inflammation,antioxidant,inhibiting vascular smooth muscle cell proliferation and apoptosis,anti-thrombosis,and dilating blood vessels.Since atherosclerosis is the pathological basis leading to cardiovascular disease and has obvious pathological stages,this text summarized the experimental studies on the mechanism of Caesalpinia sappan lignum in the process of atherosclerosis at various stages in recent years,to provide a reference for early prevention and treatment of atherosclerosis and cardiovascular diseases.
Caesalpinia sappan lignumAtherosclerosisStageMechanismExperimental research
万方数据
维普
