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系统性红斑狼疮合并弥漫性泛细支气管炎1例

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系统性红斑狼疮(SLE)是一种自身免疫性疾病,全身多系统均可受累,其中肺部是常见的受累系统之一。弥漫性泛细支气管炎(DPB)是一种双肺弥漫性的呼吸性细支气管区域的慢性炎症性疾病,若不及时诊治,最终可能会发展成呼吸衰竭甚至导致病死。目前国内尚无SLE合并DPB的病例报道,加之此类病例主要以咳嗽咳痰及活动后喘累、呼吸困难等不典型临床表现为主,难以鉴别,容易造成误诊、漏诊。本文报告 1例SLE合并DPB的治疗过程并回顾相关文献,分析此类病例的发病机制、鉴别要点,以期为临床诊治此类患者提供参考思路。
A case study of systemic lupus erythematosus complicated with diffuse panbronchiolitis
Systemic lupus erythematosus(SLE)is an autoimmune disease that affects multiple systems throughout the body,with the lungs being one of the commonly affected parts.Diffuse panbronchiolitis(DPB)is a chronic inflammatory disease characterized by diffuse respiratory bronchiolitis in both lungs.If left untreated,it may eventually develop into respiratory failure and even lead to death.At present,there are no reported cases of SLE combined with DPB in China.In addition,such cases are mainly characterized by atypical clinical manifestations such as cough,phlegm,wheezing and dyspnea after activity,etc.,making it difficult to distinguish,which can easily lead to misdiagnosis and missed diagnosis.This article reports the treatment process of a case of SLE combined with DPB and reviews relevant literature,analyzing the pathogenesis and identification points of this case,in order to provide reference ideas for clinical diagnosis and treatment of this type of patient.

Systemic lupus erythematosusDiffuse panbronchiolitisPathogenesisCase history

许潆月、戴敏、岳国龙、李延萍

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湖南中医药大学研究生院,湖南长沙 410208

重庆市中医院风湿科,重庆 400021

重庆市中医院呼吸科,重庆 400021

系统性红斑狼疮 弥漫性泛细支气管炎 发病机制 病案

李延萍重庆市名老中医药专家传承工作室建设项目重庆市自然科学基金面上项目成都中医药大学"杏林学者"医院专项

渝中医[2020]20号cstc2020jcyjmsxmX0404YYZX2022155

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(2)
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