首页|BALF-mNGS在难治性肺炎支原体肺炎中的应用1例

BALF-mNGS在难治性肺炎支原体肺炎中的应用1例

扫码查看
难治性肺炎支原体肺炎(RMPP)是肺炎支原体感染的一种严重状态。该病以发热持续时间长、住院时间长和易出现肺外并发症为特点。本文收治 1 例快速进展的肺炎支原体肺炎患儿,怀疑合并肺炎克雷伯菌感染。通过宏基因组二代测序(mNGS)确诊,使用头孢哌酮舒巴坦联合米诺环素抗感染及纤维支气管镜下肺泡灌洗治疗后,病情转归良好。病原mNGS在病原学混合感染诊断中具有重要的意义,对于RMPP患者,积极早期应用纤维支气管镜下肺泡灌洗治疗,可以明确诊断同时获得良好的治疗效果。
One case of the application of BALF-mNGS in refractory mycoplasma pneumoniae pneumonia
Refractory mycoplasma pneumoniae pneumonia(RMPP)is a serious condition of mycoplasma pneumoniae infection,characterized by a long duration of fever,prolonged hospital stay,and susceptibility to extrapulmonary complications.A case of rapidly progressing mycoplasma pneumoniae pneumonia in a child was included in this article.It was suspected to be associated with Klebsiella pneumoniae infection,which was then confirmed by metagenomic next-generation sequencing(mNGS).Cefoperazone sulbactam combined with minocycline is used for anti-infection and broncho-fiberscope alveolar lavage treatment,with a good prognosis.The mNGS of the pathogen is of great significance in the diagnosis of coinfections in etiology.For RMPP patients,it is necessary to actively apply early bronchoalveolar lavage under fiberoptic bronchoscopy,which can provide a clear diagnosis and achieve good therapeutic results.

Refractory mycoplasma pneumoniae pneumoniamNGSMycoplasma pneumoniaeCoinfections

陈映均、杨芳、刘同刚

展开 >

滨州医学院附属医院感染性疾病科,山东滨州 256603

难治性肺炎支原体肺炎 宏基因组二代测序 肺炎支原体 混合感染

山东省自然科学基金面上项目

ZR2020MH322

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(2)
  • 17