Two cases of perineal pain caused by dexamethasone sodium phosphate injection
This paper reports that two patients of the Department of Oral and Maxillofacial Surgery experienced temporary pain symptoms of the perineum after the application of dexamethasone sodium phosphate injection.Without any treatment,the symptoms quickly disappeared.Based on the five principles for determining relevance recommended in the Manual for Adverse Drug Reaction Reporting and Monitoring,this article determines that the relevance between perineal pain and adverse reactions of dexamethasone sodium phosphate injection is"affirmative".Through the literature review,the influencing factors of perineal pain caused by dexamethasone sodium phosphate injection were analyzed,with the main influencing factors considered as follows:It is related to the patient's sexual hormone levels.It is closely related to plasma concentration.Therefore,when using dexamethasone sodium phosphate injection,the dosage should be as low as possible,and the solvent shall be diluted before slow intravenous injection while ensuring the application effect.The young women and the period of 30 minutes after medication are the focuses of attention.Researchers should explore the relationship between dexamethasone sodium phosphate injection and perineal pain as well as related mechanisms as soon as possible,and study the medication route,dosage,concentration,and speed to better avoid adverse reactions of dexamethasone sodium phosphate injection,to achieve clinical medication goals and ensure patient medication safety.
DexamethasonePerineumAdverse drug reactionMedication safety
万方数据
维普
