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肌内注射地佐辛引起低血压性休克1例并文献复习

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自发性脑出血是神经内科常见的脑血管疾病类型。去骨瓣减压血肿清除术是自发性脑出血的主要治疗方式之一,但手术操作会对脑组织造成继发性损害。地佐辛是术后镇痛的阿片类药物,临床使用较为广泛。本文报告 1 例左侧基底节脑出血患者,行左侧去骨瓣减压血肿清除术,手术结束前 30 min肌内注射地佐辛注射液 5 mg,40 min后出现低血压性休克。对相关文献进行复习,以提示医生在肌内注射地佐辛时,密切关注患者的心率、血压变化,警惕低血压性休克的发生。
A case of hypotensive shock caused by intramuscular injection of dezocine and literature review
Spontaneous intracerebral hemorrhage is a common type of cerebrovascular disease in neurology.Decompressive craniectomy hematoma operation is one of the main treatment methods for spontaneous intracerebral hemorrhage,but the surgical procedure can cause secondary damage to brain tissue.Dezocine is an opioid for postoperative analgesia,which is widely used in clinical practice.A case of cerebral hemorrhage in the left basal ganglia was reported and was treated by a left decompressive craniectomy hematoma operation.In the last of 30 minutes the operation,intramuscular injection of 5 mg dezocine,hypotensive shock occurred after 40 minutes.The relevant literature was reviewed to remind doctors to pay close attention to the changes in heart rate and blood pressure of patients during the intramuscular injection of dezocine,and be alert to the occurrence of hypotensive shock.

Opioid analgesicDezocineHypotensive shockAdverse drug reaction

刘瑞玲、周俊凝、王宏彦、徐晓艳、贾晓丽、李纪尧

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山东省聊城市人民医院脑科医院药剂科,山东聊城 252000

阿片类镇痛药 地佐辛 低血压性休克 药物不良反应

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(2)
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