Research progress on the eradication of Helicobacter pylori based on the Vonoprazan regimen
Vonoprazan(VPZ)is a new type of acid-suppressing drug,with a strong and long-lasting acid inhibitory effect,superior to traditional proton pump inhibitors(PPI),and can be widely used in acid-related diseases.Currently,its main indication in China is reflux esophagitis.More and more studies have found that compared to PPI-based regimens for eradicating Helicobacter pylori(Hp),the regimen based on VPZ can improve the success rate of Hp eradication,and the adverse reactions are equivalent or even fewer.The latest domestic guidelines for the treatment of Helicobacter pylori also mention the use of VPZ,but the usage is not clear.This article summarizes the mechanism of action,usage regimen,efficacy,and safety of VPZ in the treatment of Hp infection,aiming to provide a reference for exploring the use of VPZ in the treatment of Hp infection.
国家科技期刊平台
NSTL
万方数据
