Clinical observation on treatment of knee osteoarthritis with bee venom therapy
Objective To observe the clinical efficacy of bee venom therapy on patients with knee osteoarthritis(KOA),so as to provide a new method for treating knee osteoarthritis with traditional Chinese medicine.Methods A total of 150 patients with KOA with liver and kidney deficiency who were admitted to the clinic of the Department of Traditional Chinese Medicine in Shaoxing Central Hospital and Ningbo No.2 Hospital from January 2020 to June 2023 were selected as the research object and randomly divided into the observation group and the control group,with 75 patients in each group.The treatment group was treated with bee venom therapy,while the control group was given celecoxib capsule(200 mg,qd,po,after meals);glucosamine tablets(0.75 g,bid,po,during meals).The course of treatment in both groups was 5 weeks.Before and after treatment,the scores of Western Ontario and McMaster University osteoarthritis index(WOMAC),score of visual analogue scale(VAS)of joint tenderness,VAS score of knee tenderness after 50-m walking and VAS score of joint swelling were compared between the two groups.Results A total of 137 patients completed this study,including 70 patients in the observation group and 67 patients in the control group.The total effective rate of the treatment group(82.86%)was significantly higher than that of the control group(71.64%),with statistically significant difference(P<0.05).After treatment,the VAS score of joint swelling,the VAS score of knee tenderness after 50-m walking,the VAS score of joint tenderness and the WOMAC score of the two groups were significantly lower than those before treatment,with statistically significant differences(P<0.05).After treatment,the VAS score of joint swelling,the VAS score of knee tenderness after 50-m walking,the VAS score of joint tenderness and the WOMAC score in the observation group were significantly lower than those in the control group,with statistically significant differences(P<0.05).Conclusion Bee venom therapy can obviously improve KOA-related symptoms in clinic,and it has more significant clinical effect than glucosamine tablets and celecoxib capsules.
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