摘要
目的 评估高蛋白膳食模式联合轻身汤对脾虚湿阻型肥胖患者的临床疗效.方法 选取2022年2月1日至 2023 年 2 月 1 日就诊于山西省中医院营养科的 78 例脾虚湿阻型肥胖患者,采用随机数表法分为饮食组及联合组,每组各 39 例.饮食组采用高蛋白膳食干预,联合组在饮食组的基础上加服 200 ml轻身汤,持续干预 60 d.比较两组减重有效率、平均日摄入能量、平均日摄入蛋白百分比、体重指数(BMI)、体重(BW)、腰围(M62)、体脂肪量(BFM)、内脏脂肪面积(VFA)、甘油三酯(TG)、总胆固醇(TCH)、低密度脂蛋白胆固醇(LDL)、肌酐(Cr)、尿素氮(BUN)、尿酸(UA)、中医证候积分(TCMSS).结果 联合组减重有效率高于饮食组,差异有统计学意义(P<0.05).干预后两组平均日摄入能量、BMI、BW、M62、BFM、VFA、TG、TCH、LDL、UA、TCMSS均低于干预前,差异有统计学意义(P<0.05).干预后两组平均日摄入蛋白百分比均高于干预前,差异有统计学意义(P<0.05).干预前后两组Cr、BUN比较,差异无统计学意义(P>0.05).干预后联合组平均日摄入能量、BMI、M62、BFM、VFA、TG、LDL、TCMSS均低于饮食组,差异有统计学意义(P<0.05).干预后两组BW、TCH、UA比较,差异无统计学意义(P>0.05).结论 为期 60 d的高蛋白膳食联合轻身汤治疗能显著减轻脾虚湿阻型肥胖患者的体重,改善其血脂代谢,缓解脾虚湿阻症状.
Abstract
Objective To explore the clinical therapeutic effect of a high protein diet combined with Qingshen Decoction on obese patients with spleen deficiency and dampness obstruction type.Methods A total of 78 obese patients with spleen deficiency and dampness obstruction type who visited the Department of Nutrition,Shanxi Traditional Chinese Medical Hospital from February 1,2022 to February 1,2023 were selected and divided into a diet group and a combined treatment group by random number table method,with 39 patients in each group.The diet group received intervention with a high protein diet,while the combined group received an additional 200 ml of Qingshen decoction on the basis of the intervention in the diet group.The intervention lasted for 60 days.The weight loss efficiency,average daily energy intake,average daily protein intake percentage,body mass index(BMI),body weight(BW),waist circumference(M62),body fat mass(BFM),visceral fat area(VFA),triglyceride(TG),total cholesterol(TCH),low-density lipoprotein cholesterol(LDL),creatinine(Cr),blood urea nitrogen(BUN),uric acid(UA),and traditional Chinese medicine syndrome score(TCMSS)were compared between the two groups.Results The weight loss efficiency of the combined treatment group was higher than that of the diet group,with statistically significant difference(P<0.05).After the intervention,the average daily energy intake,BMI,BW,M62,BFM,VFA,TG,TCH,LDL,UA and TCMSS of the two groups were lower than those before the intervention,with statistically significant differences(P<0.05).After the intervention,the average daily protein intake percentage of both groups was higher than that before the intervention,with statistically significant difference(P<0.05).After intervention,there was no statistically significant difference in Cr and BUN between the two groups compared to those before intervention(P>0.05).After intervention,the average daily energy intake,BMI,M62,BFM,VFA,TG,LDL,and TCMSS of the combined treatment group were lower than those of the diet group,with statistically significant differences(P<0.05).After intervention,there was no statistically significant difference in BW,TCH,and UA between the two groups(P>0.05).Conclusion A 60-day high protein diet combined with Qingshen decoction can significantly reduce the weight of obese patients with spleen deficiency and dampness obstruction type,improve blood lipid metabolism,and alleviate the symptoms of spleen deficiency and dampness obstruction.
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