The predictive value of intraoperative monitoring of regional cerebral oxygen saturation in POD in elderly patients undergoing radical resection of rectal cancer
Objective To explore the predictive value of intraoperative monitoring of regional cerebral oxygen saturation(rSO2)in postoperative delirium(POD)in elderly patients undergoing radical resection of rectal cancer.Methods A total of 88 patients who underwent radical resection of rectal cancer in the Department of Anesthesiology,Gansu Provincial Hospital from August 2022 to February 2023 were observed.rSO2,heart rate(HR),mean arterial pressure(MAP),and blood oxygen saturation(SpO2)before anesthesia induction(T0),after tracheal intubation(T1),at the beginning of surgery(T2),at 1 h after the beginning of surgery(T3),at 2 h after the beginning of surgery(T4),and at the end of surgery(T5)were monitored after included.rSO2 at T0 was considered as the baseline value,to calculate the minimum value(rSO2min),mean value(rSO2mean),and maximum difference decreased from the baseline value(rSO2%max)of rSO2.After surgery,patients were divided into a POD group and a non-POD group based on the presence or absence of POD.HR,MAP,SpO2,and rSO2 were compared between the two groups.Results The HR,MAP,and SpO2 at T0,T1,T2,T3,T4,and T5,and rSO2 at T0,T1 and T2 between the POD group and the non-POD group were compared,without statistically significant differences(P>0.05).The rSO2 at T3,T4,and T5in the POD group were lower than those in the non-POD group,with statistically significant difference(P<0.05).The rSO2 baseline value was compared between the POD group and the non-POD group,without statistically significant difference(P>0.05).The rSO2 min and rSO2 mean in the POD group were lower than those in the non-POD group,while the rSO2%max in the POD group was higher than that in the non-POD group,with statistically significant differences(P<0.05).Conclusion The decrease in rSO2 is associated with POD in elderly patients undergoing radical resection of rectal cancer,and rSO2 can be used as a predictor of POD.
Regional cerebral oxygen saturationElderlyRadical resection of rectal cancerDelirium