中国医药科学2024,Vol.14Issue(6) :151-154.DOI:10.20116/j.issn2095-0616.2024.06.35

置管部位对我国血液病患者PICC相关性血栓影响的meta分析

Meta-analysis of the impact of catheterization sites on PICC-related thrombosis in Chinese patients with hematological diseases

苏醒 马银鑫 邵帅
中国医药科学2024,Vol.14Issue(6) :151-154.DOI:10.20116/j.issn2095-0616.2024.06.35

置管部位对我国血液病患者PICC相关性血栓影响的meta分析

Meta-analysis of the impact of catheterization sites on PICC-related thrombosis in Chinese patients with hematological diseases

苏醒 1马银鑫 1邵帅1
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作者信息

  • 1. 中国医学科学院血液病医院(中国医学科学院血液学研究所)实验血液学国家重点实验室国家血液系统疾病临床医学研究中心 细胞生态海河实验室 天津医学健康研究院,天津 300020
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摘要

目的 系统评价置管部位对我国血液病患者经外周静脉置入中心静脉导管术后相关性血栓的影响,为临床提供借鉴依据.方法 检索中英文数据库,时限为2001年1月1日至2023年1月1日,将检索的文献交由2名专业人员筛选与评价,最终纳入的文献采用Review Manager 5.3进行meta分析.结果 共纳入9篇文献,总累计病例组188例、对照组1340例,涉及4项影响因素.meta分析结果 显示:贵要静脉[OR=0.63,95%CI(0.43,0.94)、P=0.02]、头静脉[OR=2.45,95%CI(1.39,4.34),P=0.002]、置管肢体[OR=0.63,95%CI(0.41,0.96),P=0.03]同其他比较,差异有统计学意义(P<0.05).结论 贵要静脉、左侧置管可降低我国血液病患者导管相关性血栓的发生率,为保护因素;头静脉及右侧置管为危险因素.

Abstract

Objective To systematically evaluate the impact of catheterization sites on related thrombosis in Chinese patients with hematological diseases after peripherally inserted central catheter,and to provide a reference for clinical practice.Methods The Chinese and English databases were retrieved,with the retrieval duration from January 1,2001 to January 1,2023.The retrieved literature was screened and evaluated by two professionals,and a meta-analysis was conducted on the final included literature using Review Manager 5.3.Results A total of 9 articles were included,with a total of 188 patients in the case group and 1340 patients in the control group,involving 4 influencing factors.The meta-analysis results showed that the basilic vein(OR=0.63,95%CI[0.43,0.94],P=0.02),cephalic vein(OR=2.45,95%CI[1.39,4.34],P=0.002),and the limb for catheterization(OR=0.63,95%CI[0.41,0.96],P=0.03)showed statistically significant difference(P<0.05).Conclusion The basilic vein and left catheterization can reduce the incidence of PICC-related VT in patients with hematological diseases in China,being protective factors.The cephalic vein and right catheterization are risk factors.

关键词

血液病/经外周静脉置入中心静脉导管/血栓/meta分析

Key words

Hematological disease/Peripherally inserted central catheter/Thrombosis/meta-analysis

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基金项目

中国医科院医学与健康科技创新工程项目(2021-I2M-C&T-B-085)

出版年

2024
中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
参考文献量21
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