Meta-analysis of the clinical efficacy and safety of Shenqi Dihuang Decoction in the treatment of chronic kidney disease
Objective To systematically evaluate the clinical efficacy and safety of Shenqi Dihuang Decoction in the treatment of chronic kidney disease(CKD).Methods Randomized controlled trials(RCT)for the treatment of CKD with Shenqi Dihuang Decoction were retrieved in databases such as CNKI,Wanfang,VIP,CBM,and PubMed,with the retrieval time limit from the establishment of the database to February 2023.RevMan 5.4 software was used for quality evaluation and meta-analysis.Results A total of 10 studies were included,involving and 722 patients.The meta-analysis results showed that the total effective rate and endogenous creatinine clearance rate of the test group were higher than those of the control group,while the serum creatinine,blood urea nitrogen,24-hour urine protein quantification,and adverse reaction rate of the test group were lower than those of the control group,with differences were statistically significant(P＜0.05).Conclusion Shenqi Dihuang Decoction has good clinical efficacy and safety in the treatment of CKD,not limited to deficiency of qi and yin.
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