Analysis of the application value of magnetic resonance 3D-ASL technology combined with ABCD2 score in transient ischemic attacks of the anterior circulation
Objective To explore the application value of three dimensioned-arterial spin labeling(3D-ASL)technology in combination with ABCD2 score in the treatment of transient ischemic attack(TIA)of the anterior circulation.Methods A total of 64 patients diagnosed with TIA of the anterior circulation at Hongqi Hospital affiliated to Mudanjiang Medical University from May 2021 to December 2022 were selected.They completed various magnetic resonance imaging examinations,with the post label delay(PLD)of dual-phase 3D-ASL being 1.5 s and 2.5 s respectively,and completed the ABCD2 score as well as a 90-day follow-up.3D-ASL images were analyzed,cerebral blood flow(CBF)was measured,and relative cerebralblood flow(rCBF)was calculated to analyze the application value of 3D-ASL and ABCD2 scores on evaluation of the conditions and prognosis of TIA patients.Results The PLD = 1.5 s,CBF and rCBF are both lower than PLD = 2.5 s.rCBF is negatively correlated with ABCD2 score.The 3D-ASL detection rate of abnormalities in TIA patients is higher than MRA detection rate.The incidence of cerebral infarction in the 3D-ASL detected abnormality group was higher than that in the normal group.There are differences in the incidence of cerebral infarction among different risk groups,with a statistically significant difference.The ROC curve analysis results show that the combination of 3D-ASL technology and ABCD2 score has the maximum area under the curve(AUC)of 0.907 for the 90-day prognosis of TIA patients.Conclusion Dual-phase 3D-ASL can detect subtle perfusion changes in TIA patients,reflect compensatory blood supply conditions,and serve as a further examination method for TIA patients.In combination with ABCD2 score,dual-phase 3D-ASL can effectively predict the 90-day prognosis of TIA patients and has significant clinical application value.
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