Study on risk factors for frequent ventricular premature beats in STEMI patients after emergency PCI
Objective To explore the risk factors of frequent ventricular premature beats(VPBs)after emergency percutaneous coronary intervention(PCI)in patients with ST-elevated myocardial infarction(STEMI).Methods A total of 108 STEMI patients who visited the Chest Pain Center of Hainan Hospital of Traditional Chinese Medicine from July 2021 to July 2023 were selected and included in this study.All patients were divided into two groups based on whether they had frequent ventricular premature beats within one week after emergency PCI,namely the frequent ventricular premature beat group(n=25)and the nonfrequent ventricular premature beat group(n=83).Then,baseline data,emergency PCI data,and serum 8-hydroxy-deoxyguanosine(8-OHDG)levels after PCI of all patients at admission were recorded for statistical analysis.Results In terms of baseline data,there was no statistically significant difference between the two groups of patients in terms of age,gender,history of smoking and drinking habits,vital signs,Killip grade,electrolyte levels,and left ventricular ejection fraction(P＞0.05).The number of patients with diabetes mellitus in the frequent ventricular premature beat group was significantly higher than that in the nonfrequent ventricular premature beat group,with statistically significant difference(P＜0.05).There was no statistically significant difference between the two groups of patients in the time from the onset of STEMI to the arrival of the hospital gate,the time from the hospital gate to the passage of the guide wire,troponin I,brain natriuretic peptide,myoglobin,creatine kinase isoenzyme,whether it was a three vessel lesion,and whether it was a proximal lesion of the left main or anterior descending branch(P＞0.05).In addition,the serum 8-OHDG levels in the frequent ventricular premature beat group after PCI were significantly higher than those in the nonfrequent ventricular premature beat group,with statistically significant difference(P＜0.05).Bivariate logistic regression analysis showed that the history of diabetes mellitus and the high level of 8-OHDG after PCI were the risk factors for frequent ventricular premature beats after emergency PCI in STEMI patients(P＜0.05).Conclusion The history of diabetes mellitus and the high level of 8-OHDG after PCI are the risk factors for frequent ventricular premature heats after emergency PCI in STEMI patients.
万方数据
维普
