A retrospective analysis was conducted on the diagnosis and treatment process and clinicopathological data of a case of aggressive fibromatosis(AF)in the neck after surgery for papillary thyroid carcinoma(PTC).The patient,a 25-year-old female,underwent radical left PTC resection in 2021,and the re-examination of thyroid color ultrasound showed a right thyroid fusiform hypoechoic nodule,and the gross needle aspiration was considered to be a fibrous tissue proliferative lesion,and genetic testing showed HR AS and KRAS gene mutations.Upon re-admission to the hospital,a right cervical mass resection was performed,and AF was confirmed by postoperative pathology.Based on domestic and foreign literature,the diagnosis and treatment experience of this disease and its characteristics were summarized,to provide a reference for clinical workers to better understand its pathogenesis,diagnosis,and treatment.It was found that patients with postoperative cervical AF often exhibit local invasion and a high local recurrence rate.Watch and Wait is a first-line treatment method.After comprehensive evaluation,surgical treatment should be taken for progressive masses,while systemic treatment should be taken if surgical treatment is difficult to be conducted.
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