This article reviews the medical records of 5 patients with hereditary hypofibrinogenemia combined with pregnancy and explores the management of the delivery period for hereditary hypofibrinogenemia combined with pregnancy.Based on the literature,patients with hereditary hypofibrinogenemia combined with pregnancy who received fibrinogen or cryoprecipitate replacement therapy during the delivery period can prevent from postpartum hemorrhage;It is also feasible to choose vaginal delivery under close supervision.During pregnancy,it is necessary to closely monitor patients for bleeding tendencies,regularly detect changes in coagulation indicators,develop personalized management plans,and perform replacement treatment if necessary.
关键词
妊娠/遗传性/低纤维蛋白原血症/凝血功能
Key words
Pregnancy/Hereditary/Hypofibrinogenemia/Coagulation function