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遗传性低纤维蛋白原血症合并妊娠5例报道

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本文通过对遗传性低纤维蛋白原血症合并妊娠的5例患者病例资料进行回顾,探讨遗传性低纤维蛋白原血症合并妊娠的分娩期处理。结合文献,在分娩期给予遗传性低纤维蛋白原血症合并妊娠患者纤维蛋白原或冷沉淀替代治疗可预防产后出血;密切监护下选择经阴道分娩是可行的。孕期需严密观测患者有无出血倾向,定期检测凝血指标变化,个体化制订管理方案,必要时行替代治疗。
A report of 5 cases of hereditary hypofibrinogenemia complicated with pregnancy
This article reviews the medical records of 5 patients with hereditary hypofibrinogenemia combined with pregnancy and explores the management of the delivery period for hereditary hypofibrinogenemia combined with pregnancy.Based on the literature,patients with hereditary hypofibrinogenemia combined with pregnancy who received fibrinogen or cryoprecipitate replacement therapy during the delivery period can prevent from postpartum hemorrhage;It is also feasible to choose vaginal delivery under close supervision.During pregnancy,it is necessary to closely monitor patients for bleeding tendencies,regularly detect changes in coagulation indicators,develop personalized management plans,and perform replacement treatment if necessary.

PregnancyHereditaryHypofibrinogenemiaCoagulation function

何颖、杨培峰、刘鹏丽、高如双

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郑州大学第三附属医院产科,河南郑州 450052

妊娠 遗传性 低纤维蛋白原血症 凝血功能

2024

中国医药科学
海峡两岸医药卫生交流协会 二十一世纪联合创新(北京)医药科学研究院

中国医药科学

影响因子:1.083
ISSN:2095-0616
年,卷(期):2024.14(8)
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